Interstitial Cystitis Specialist

Dr. Daniel Stone, MD FACOG

Urogynecologist located in Phoenix, AZ

Dr. Daniel Stone, MD is one of the leading experts in the management of bladder pain, bladder pain syndrome and interstitial cystitis. Dr. Stone can diagnosis and provides management options for interstitial cystitis to patients in the Phoenix, Scottsdale and surrounding Arizona areas.

Interstitial Cystitis Q&A

  • What is Bladder Pain Syndrome or Interstitial Cystitis?

    Bladder Pain Syndrome or Interstitial cystitis is a condition characterized by pain, burning, pressure or an unpleasant sensation in the bladder that often occurs with urgency and frequency. Symptoms can vary from woman to woman. Most women experience increasing discomfort as the bladder fills. Many women feel a constant need to empty their bladder. Symptoms often get worse during menstruation or times of emotional stress.

    This condition occurs in 3-7% of women and is most commonly diagnosed in women in their 40s. 

  • What is the cause of Bladder Pain Syndrome or Interstitial Cystitis?

    The cause of Bladder Pain Syndrome or Interstitial Cystitis is unknown. It is likely due to multiple factors including genetics, damage to the bladder wall, hypersensitive bladder nerves, and an allergic component as well.

  • How common is Interstitial Cystitis?

    Approximately 2-6% of women in the United States have symptoms consistent with Interstitial cystitis. However, less than 1% have received a diagnosis of Interstitial cystitis. 

  • How is Bladder Pain Syndrome or Interstitial Cystitis diagnosed?

    The diagnosis of Bladder Pain Syndrome or Interstitial Cystitis is a diagnosis of exclusion, meaning that once other causes are ruled out, Dr. Stone will make a presumptive diagnosis of Bladder Pain Syndrome or Interstitial Cystitis.

    Dr. Stone will first talk to you about your symptoms and how they started and what helps the pain and what makes it worse. He will then perform an exam looking for any other cause of the pain. He will also test the urine to rule out a urinary tract infection. Depending on the results of these findings and tests, he may suggest additional testing such as a cystoscopy or urodynamics.

  • How is Bladder Pain Syndrome or Interstitial Cystitis treated?

    Dr. Stone will discuss a variety of treatments with you. Currently, there is no cure for Bladder Pain Syndrome or Interstitial Cystitis. The goal of any treatment is to better manage the pain and reduce the number of "flares". 


    Women with Bladder Pain Syndrome or Interstitial Cystitis usually find that their symptoms vary based on certain foods and drinks that they ingest. Identifying these trigger foods is key to reducing the number of flares. Keeping a food diary can be very helpful in doing this. Dr. Stone will discuss with you common foods that are known to cause flares. Typically he recommends eliminating all of the following foods and slowly reintroducing these foods to identify trigger foods.

    • Fruits (juice or fruit)
      • Cranberries
      • Grapefruits
      • Lemons
      • Oranges
      • Pineapples
    • Vegetables
      • Peppers
      • Pickles
      • Sauerkraut
      • Tomatoes
    • Condiments
      • Chili
      • Horseradish
      • Salad Dressing
      • Vinegar
    • Drinks
      • Coffee (both caffeinated and decaf)
      • Tea (both caffeinated and decaf)
      • Carbonated drinks
      • Alcohol (especially beer, and red wine)
    • Other & Additives
      • Chocolate
      • Indian Food
      • Mexican Food
      • Thai Food
      • Spicy Food
      • MSG
      • Artificial sweeteners

    Stress Management

    For most women stress makes the symptoms worse and brings on flares more frequently. Avoiding stress is much easier said than done. Yoga, exercise, hypnosis, acupuncture, taking walks all have been shown to help manage stress but ultimately you will need to find how best to manage the stress in your life. 

    Physical Therapy

    There are specially trained physical therapists that specialize in the pelvic floor. They can manually maneuver the muscles surrounding the bladder and relax these muscles and help relieve pain. Dr. Stone has a list of pelvic floor physical therapists throughout Arizona and he will discuss this option with you if you desire. This type of therapy will be different than strengthening the pelvic floor through pelvic floor muscle exercises (aka Kegels)


    Dr. Stone will discuss with you different medications that can be used to treat Bladder Pain Syndrome or Interstitial Cystitis. 

    • Pentosan Polysulfate Sodium (Elmiron) is the only FDA approved medication for Bladder Pain Syndrome or Interstitial Cystitis. It helps heal the bladder lining. In the past, Dr. Stone has used this as a first line medication. However, there have been recent reports of damage to the eye with long-term use. Dr. Stone will discuss this medication with you but is now more cautious in prescribing it and now recommends seeing a ophthalmologist if prescribed.
    • Amitriptyline is an older medication that is used to treat Bladder Pain Syndrome or Interstitial Cystitis. This medication effects the nerves of the bladder and helps reduce the nerve sensitivity to pain. Dr. Stone will slowly go up with the dosage until the right dose is found.
    • Hydroxyzine is an antihistamine and can be considered.
    • Cimetidine is an antihistamine used for heartburn and can also be considered

    Bladder Instillation

    Dr. Stone may suggest placing a solution of medications into the bladder if oral medications fail. This solution is a mix of heparin, lidocaine, and kenalog. This is done in a series of installations, usually once a week for 6-8 weeks.

    Cystoscopy with Hydrodistension

    This is a procedure that is done under anesthesia. Dr. Stone will fill up the bladder with saline and stretch the nerve fibers in the bladder for a short period of time. He then looks at the bladder wall for signs of ulcerations. This procedure is both therapeutic and occasionally diagnostic if a certain type of ulcer called a Hunner's Ulcer is seen. 

    Sacral Nerve Stimulation

    Electrical stimulation to the sacral nerves can help with pain, urgency, and frequency. This can be done by implanting a device near the buttocks which delivers this stimulation.

    Bladder Botox

    Botox injection into the bladder wall can help increase the bladder capacity and reduce urgency and frequency. This is a procedure that is done in the office with local anesthesia and using a small camera and a very small needle the bladder wall is injected with botox. These injections tend to last 6-12 months.


Created by potrace 1.15, written by Peter Selinger 2001-2017backgroundLayer 1Read More
"He actually took the time and listened to me. After the exam he told me that he wanted to try another pessary before committing to surgery. He fit one in and it worked! I haven't felt this good in years. I'm so so grateful to him!"
Created by potrace 1.15, written by Peter Selinger 2001-2017backgroundLayer 1Read More
"He is one of the most caring docs I've ever been to. I've been struggling with this problem for years and have been to 3 docs before I saw him."
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"Dr. Stone is a really good doctor. After I had the urethra sling surgery Dr Stone called me at home to see how I was doing. The office staff is good. Dr Stone's nurse Iris is really good she returns calls. I will refer my family and friends to this office."
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"Dr. Stone has been wonderful. I was very hesitant at first to see a man but he put me completely at ease. I was able to speak to him about my problem with leakage. He discussed several options and gave me choices which I loved. Eventually I decided on surgery. The surgery went well and I finally have my life back again."
Created by potrace 1.15, written by Peter Selinger 2001-2017backgroundLayer 1Read More
"I highly recommend him. I will be referring all my loved ones if ever they develop problems."
Created by potrace 1.15, written by Peter Selinger 2001-2017backgroundLayer 1Read More
"He put us at ease about the surgery by really explaining the procedure in detail to me, my husband and my daughter. He made me feel like I was his only patient."
Created by potrace 1.15, written by Peter Selinger 2001-2017backgroundLayer 1Read More
"Awesome!! Would give him 10 stars!!!!! Dr. Stone took the time to fully explain medical procedures. He patiently answered all my questions."
Created by potrace 1.15, written by Peter Selinger 2001-2017backgroundLayer 1Read More
"His bed-side manner put me at ease discussing a very embarrassing topic. I'd recommend him to anyone."

Major Insurance Providers Accepted

We accept most insurance policies for your convenience. Please contact your insurance carrier to verify your individual benefits and any copays or coinsurance that are part of your plan. Patients are responsible for notifying our office if a specific plan requires precertification, preauthorization, or a referral (especially HMOs). Please call the phone number on the back of your insurance card to verify your provider network participation as insurance carriers change policies often.

Schedule your appointment with Dr. Stone today

One of our staff members will contact you directly. If you have any concerns requiring immediate attention, please don’t hesitate to call us at 602-788-1521.

Office location

Valley Urogynecology Associates

1616 East Maryland Avenue

Phoenix, Arizona 85016-1302

Office Hours: Monday-Friday from 8 AM – 5 PM

Main: (602) 788-1521

Fax: (602) 688-5420

Conveniently located just off Highway 51 on Maryland Avenue just East of 16th Street between East Bethany Home Road and East Glendale Avenue.